Botox Usage Safety
Shared by Zenith Health
Pearl found
20 sources
with relevant information, from which
7 peer-reviewed research articles
3 articles from healthcare institutions
10 general health and web sources
are cited in Pearl's summary below.
Overview:The evidence collected indicates that the use of Botox during pregnancy is a topic with limited and mixed research. While some studies suggest that Botox may be relatively safe for both the mother and fetus, particularly when used for medical purposes, others recommend caution due to the lack of comprehensive data on its effects during pregnancy. The FDA classifies Botox as a Category C drug, meaning there are no adequate and well-controlled studies in pregnant women, and it should only be used during pregnancy if the benefits outweigh the potential risks.
Findings:
- Safety Concerns:The primary concern with using Botox during pregnancy is the potential for the botulinum toxin to cross the placenta and affect the fetus. However, studies suggest that the toxin does not enter the bloodstream in large amounts and is unlikely to reach the baby.
- Medical vs. Cosmetic Use:While cosmetic use of Botox during pregnancy is generally discouraged due to the lack of clinical benefit to the mother, its use for medical conditions such as chronic migraines or severe muscle spasms may be considered if the benefits outweigh the risks.
- Limited Data:The available data on Botox use during pregnancy is limited, with most studies involving small sample sizes and lacking comprehensive long-term outcomes.
- Alternative Treatments:For cosmetic purposes, alternative treatments such as topical treatments or facials designed for pregnant women are recommended.
Conclusion:The evidence suggests that while Botox may be relatively safe for medical use during pregnancy, its cosmetic use is generally discouraged due to the lack of clinical benefit and insufficient data on its safety. It is important to consult with a healthcare provider to weigh the potential benefits and risks before considering Botox during pregnancy. For cosmetic concerns, alternative treatments should be considered.
Peer-Reviewed Research
Published, peer-reviewed scientific studies from journals or databases.
Published, peer-reviewed scientific studies from journals or databases.
1
2
3
6
7
13
14
Clinical Guidelines & Professional Sources
Clinical recommendations from government, public health organizations, or professional medical provider associations.
Clinical recommendations from government, public health organizations, or professional medical provider associations.
Medical & Academic Institutions
Information from hospitals, research institutions, or academic medical centers known for clinical expertise and research contributions.
Information from hospitals, research institutions, or academic medical centers known for clinical expertise and research contributions.
4
5
8
General Health & Web Sources
Publicly available health-related articles from non-peer-reviewed sources. These may reference research or clinical guidelines, but are not primary sources.
Publicly available health-related articles from non-peer-reviewed sources. These may reference research or clinical guidelines, but are not primary sources.
9
10
11
12
15
16
17
18
19
20
Uncategorized Sources
Information from sources that have not yet been categorized.
Information from sources that have not yet been categorized.
Can You Get Botox While Pregnant? Safety and Alternatives
If you’ve been using Botox for a while, you probably don’t think too much about it anymore, other than to make sure you’ve budgeted for it. Generally, research shows that botulinum toxin injections for erasing those annoying parallel lines between your eyebrows are safe for most people. However, a positive pregnancy ...
Read full article
Source:
Healthline
You Shouldn't Get Botox While Pregnant, According to Several Physicians
Botox is a popular cosmetic treatment, but is it safe during pregnancy? Here, dermatologists and an OB/GYN weigh in on why they don't recommend it.
Read full article
Source:
Byrdie
Botox (botulinum toxin)
If Botox is correctly injected, it should stay in the muscles being treated and would therefore not be expected to cause problems for the baby. However, as a precaution, cosmetic treatments with Botox are not recommended during pregnancy as there is no clinical benefit to these treatments.
Injectables and Pregnancy: 2022 Precautions
We all spend a lot of time on our appearance and it’s something we take pride in. But, where do we draw the line when it comes to injectables and pregnancy? Is it safe to get Botox while pregnant? Will it harm the baby?
Why Botox Isn’t Recommended During Pregnancy
Botox hasn’t been shown to be harmful during pregnancy. But it hasn’t proven to be safe either. Try these other methods to keep your skin in tip-top shape while pregnant.
Read full article
Source:
Cleveland Clinic
Can you get Botox while pregnant? | BabyCenter
It's unlikely there's any risk to your baby. But if you're deciding whether or not to get Botox while you're pregnant or nursing, it's best to err on the side of caution and wait. ... The good news is many women report that their migraines are less severe during pregnancy.
Read full article
Source:
BabyCenter
Can You Get Botox While Pregnant? | Metropolitan Skin Clinic
Despite the research that has been conducted on this topic thus far, there isn’t conclusive data on whether or not you can do Botox while pregnant. According to a 2017 review of cosmetic procedure safetyduringpregnancy and breastfeeding, there haven’t been any clinical trials that examine ...
Frontiers | Safety of OnabotulinumtoxinA in the [management of] chronic migraine in pregnancy
OnabotulinumtoxinA is an irreversible acetylcholinesterase inhibitor and neuromuscular blocking agent first approved for use by the FDA in 1989, and most rec...
Read full article
Source:
Frontiers
Why You Shouldn't Keep Getting Botox While You're Pregnant | Allure
The injectable is not recommended by any of our experts: "According to the FDA, Botox is a category C drug during pregnancy," says board-certified dermatologist Kim Nichols, MD, FAAD, who explains that this means there are not a sufficient number of studies to show its safety during pregnancy.
Read full article
Source:
Allure
EXPOSURE TO BOTULINUM TOXIN IN PREGNANCY – UKTIS
There are limited data on which to base an assessment of the safety of BTX-A in human pregnancy. Animal studies of exposure to high doses of BTX-A have demonstrated teratogenic risk. Data from human pregnancies exposed to Clostridium botulinum infection or to BTX-A do not raise concern of adverse ...
Read full article
Source:
uktis.org
Why You Shouldn't Get Botox While Pregnant - Skin Therapeutics Med Spa
Learn Why BotoxDuringPregnancy Is a Risk, FDA's Classification, and Safe Alternatives to Maintain Skin Health for Expectant Mothers.
Can I Get Botox If I’m Pregnant? | Eyesthetica
In summary, studies (although few) have shown that Botox can be safely administered during pregnancy. This is because the amount of Botox injected is small, and Botox injected into the facial muscles stay within that muscle without circulating throughout the body.
Read full article
Source:
Eyesthetica
Botulinum toxin A during pregnancy: a survey of treating physicians - PMC
Botulinum toxin A (btxA) is widely used for cosmetic purposes, headaches, dystonia, spasticity, pain and other on and off label uses. Despite the widespread use of btxA in women of childbearing potential, there are few data on the effects of this drug ...
Read full article
Source:
ncbi.nlm.nih.gov
Botulinum toxin type A in pregnancy - PMC
Question My patient received 62 units of botulinum toxin type A (BTX-A) for facial lines. Two weeks later, she found out that she was pregnant. Will this cause any harm to her fetus? Answer Botulinum toxin is not expected to be present in systemic ...
Pregnancy Outcomes in Patients Exposed to OnabotulinumtoxinA Treatment | Neurology
Brin MF. Development of future indications for BOTOX. Toxicon. 2009;54(5):668-674. ... Brin MF, Kirby RS, Slavotinek A, et al. Pregnancy outcomes following exposure to onabotulinumtoxinA. Pharmacoepidemiol Drug Saf.
Read full article
Source:
Neurology
BOTOX for migraines, and more pregnancy-safe treatment options | Your Pregnancy Matters | UT Southwestern Medical Center
Many migraine treatments are proven to be generally safe and effective during pregnancy, including BOTOX®. Yes, this cosmetic injection to reduce the appearance of wrinkles can relieve certain types of migraines.
Pregnancy outcomes following exposure to onabotulinumtoxinA - PMC
OnabotulinumtoxinA is designated as a US Food and Drug Administration (FDA) pregnancy category C pharmaceutical product, as there are no adequate and well controlled studies in pregnant women, and it should only be used during pregnancy if the benefits outweigh the potential risks.3 While women ...
Read full article
Source:
ncbi.nlm.nih.gov
Botox and Pregnancy: Safety, Risks and Alternatives
Stop wondering “Can I get Botox while pregnant?” Learn what medical research says about Botox and safety, potential risks and alternatives.
Read full article
Source:
The Bump
Botulinum toxin A during pregnancy: a survey of treating physicians - PMC
The woman who was injected with btxA during three separate pregnancies received 1–3 injections during each pregnancy, occurring over all three trimesters (approximately 300 U per treatment). The injected btxA dose ranged from 1.25 U to 300 U (of the Botox formulation).
OnabotulinumtoxinA for chronic migraine during pregnancy: a real world experience on 45 patients | The Journal of Headache and Pain | Full Text
Robinson AY, Grogan PM (2014) OnabotulinumA successfully used as a migraine prophylaxis during pregnancy: a case report. Mil Med 179(6):703–704 ... Khalil M, Zafar HW, Quarshie V, Ahmed F (2014) Prospective analysis of the use of OnabotulinumtoxinA (Botox) in the treatment of chronic migraine; ...